lucille
- June 2, 2022
- 0 Comments
Biological Properties, Pathogenesis and Pathology of the Influenza Virus
Biological Properties, Pathogenesis and Pathology of the Influenza Virus
HemagglutininAll strains of influenza virus agglutinate erythrocytes from chickens, guinea pigs and humans and-unlike paramyxo viruses-agglutinate erythrocytes from many other species as well Agglutination of red blood cells occurs when the hemagglutinin interacts with a specific receptor on the red blood cell membrane. This receptor is a glycoprotein that contains sialic acid. This glycoprotein serves both as the receptor site for the hemagglutin and as the substrate for the viral neuraminidase, Cleavage of the glycoprotein by the enzyme dissociates the virion from the red cell, resulting in spontaneous elution. After elution, …
